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However, subsequent trials yielded mixed findings

They recognize that clinical trials showed modest effects (average 2.6 kg over 12 weeks in responders), appreciate that individual response varies significantly, commit to proper nutrition and exercise foundations, and accept that the peptide is used for research purposes under medical supervision

The FDA Pharmacy Compounding Advisory Committee reviewed ipamorelin in October 2024 but compounding eligibility review is not the same as drug approval [8]